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reference ido1 inhibitor epacadostat  (BPS Bioscience)


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    Structured Review

    BPS Bioscience reference ido1 inhibitor epacadostat
    Effect of the investigated lichen extracts and reference compounds on the activity of indoleamine-2,3-dioxygenase <t> (IDO1, </t> IDO2) and tryptophan-2,3-dioxygenase (TDO).
    Reference Ido1 Inhibitor Epacadostat, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/reference ido1 inhibitor epacadostat/product/BPS Bioscience
    Average 90 stars, based on 1 article reviews
    reference ido1 inhibitor epacadostat - by Bioz Stars, 2026-03
    90/100 stars

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    1) Product Images from "Lichen-Derived Compounds and Extracts as Biologically Active Substances with Anticancer and Neuroprotective Properties"

    Article Title: Lichen-Derived Compounds and Extracts as Biologically Active Substances with Anticancer and Neuroprotective Properties

    Journal: Pharmaceuticals

    doi: 10.3390/ph14121293

    Effect of the investigated lichen extracts and reference compounds on the activity of indoleamine-2,3-dioxygenase  (IDO1,  IDO2) and tryptophan-2,3-dioxygenase (TDO).
    Figure Legend Snippet: Effect of the investigated lichen extracts and reference compounds on the activity of indoleamine-2,3-dioxygenase (IDO1, IDO2) and tryptophan-2,3-dioxygenase (TDO).

    Techniques Used: Activity Assay, Inhibition

    The biological activity of lichen-derived compounds and extracts: compounds ( A ) and extracts ( B ), expressed by the surface of area, taking into account the measured biological properties expressed in %. The graphs were made for the concentrations: inhibition of IDO1 100.0 µg/mL ( A , B ); inhibition of COX-2 250.0 µg/mL ( A , B ); inhibition of hyaluronidase 500.0 µg/mL ( A , B ); inhibition of SOD 537.6 µg/mL ( A , B ); inhibition of GR 444.4 µg/mL ( A , B ); inhibition of GPx 243.9 µg/mL ( A , B ); cytotoxicity expressed as % of cell death: A-172 100 µM ( A ), 50 µg/mL ( B ), and T98G 100 µM ( A ), 50 µg/mL ( B ).
    Figure Legend Snippet: The biological activity of lichen-derived compounds and extracts: compounds ( A ) and extracts ( B ), expressed by the surface of area, taking into account the measured biological properties expressed in %. The graphs were made for the concentrations: inhibition of IDO1 100.0 µg/mL ( A , B ); inhibition of COX-2 250.0 µg/mL ( A , B ); inhibition of hyaluronidase 500.0 µg/mL ( A , B ); inhibition of SOD 537.6 µg/mL ( A , B ); inhibition of GR 444.4 µg/mL ( A , B ); inhibition of GPx 243.9 µg/mL ( A , B ); cytotoxicity expressed as % of cell death: A-172 100 µM ( A ), 50 µg/mL ( B ), and T98G 100 µM ( A ), 50 µg/mL ( B ).

    Techniques Used: Activity Assay, Derivative Assay, Inhibition



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    BPS Bioscience reference ido1 inhibitor epacadostat
    Effect of the investigated lichen extracts and reference compounds on the activity of indoleamine-2,3-dioxygenase <t> (IDO1, </t> IDO2) and tryptophan-2,3-dioxygenase (TDO).
    Reference Ido1 Inhibitor Epacadostat, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/reference ido1 inhibitor epacadostat/product/BPS Bioscience
    Average 90 stars, based on 1 article reviews
    reference ido1 inhibitor epacadostat - by Bioz Stars, 2026-03
    90/100 stars
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    Effect of the investigated lichen extracts and reference compounds on the activity of indoleamine-2,3-dioxygenase  (IDO1,  IDO2) and tryptophan-2,3-dioxygenase (TDO).

    Journal: Pharmaceuticals

    Article Title: Lichen-Derived Compounds and Extracts as Biologically Active Substances with Anticancer and Neuroprotective Properties

    doi: 10.3390/ph14121293

    Figure Lengend Snippet: Effect of the investigated lichen extracts and reference compounds on the activity of indoleamine-2,3-dioxygenase (IDO1, IDO2) and tryptophan-2,3-dioxygenase (TDO).

    Article Snippet: Inhibitory effects of the investigated extracts and standards (salazinic acid, evernic acid, (−)-usnic acid), as well as the reference IDO1 inhibitor (epacadostat) were determined using Universal IDO1/IDO2/TDO Inhibitor Screening Assay Kit from BPS Bioscience, Inc. (San Diego, CA, USA).

    Techniques: Activity Assay, Inhibition

    The biological activity of lichen-derived compounds and extracts: compounds ( A ) and extracts ( B ), expressed by the surface of area, taking into account the measured biological properties expressed in %. The graphs were made for the concentrations: inhibition of IDO1 100.0 µg/mL ( A , B ); inhibition of COX-2 250.0 µg/mL ( A , B ); inhibition of hyaluronidase 500.0 µg/mL ( A , B ); inhibition of SOD 537.6 µg/mL ( A , B ); inhibition of GR 444.4 µg/mL ( A , B ); inhibition of GPx 243.9 µg/mL ( A , B ); cytotoxicity expressed as % of cell death: A-172 100 µM ( A ), 50 µg/mL ( B ), and T98G 100 µM ( A ), 50 µg/mL ( B ).

    Journal: Pharmaceuticals

    Article Title: Lichen-Derived Compounds and Extracts as Biologically Active Substances with Anticancer and Neuroprotective Properties

    doi: 10.3390/ph14121293

    Figure Lengend Snippet: The biological activity of lichen-derived compounds and extracts: compounds ( A ) and extracts ( B ), expressed by the surface of area, taking into account the measured biological properties expressed in %. The graphs were made for the concentrations: inhibition of IDO1 100.0 µg/mL ( A , B ); inhibition of COX-2 250.0 µg/mL ( A , B ); inhibition of hyaluronidase 500.0 µg/mL ( A , B ); inhibition of SOD 537.6 µg/mL ( A , B ); inhibition of GR 444.4 µg/mL ( A , B ); inhibition of GPx 243.9 µg/mL ( A , B ); cytotoxicity expressed as % of cell death: A-172 100 µM ( A ), 50 µg/mL ( B ), and T98G 100 µM ( A ), 50 µg/mL ( B ).

    Article Snippet: Inhibitory effects of the investigated extracts and standards (salazinic acid, evernic acid, (−)-usnic acid), as well as the reference IDO1 inhibitor (epacadostat) were determined using Universal IDO1/IDO2/TDO Inhibitor Screening Assay Kit from BPS Bioscience, Inc. (San Diego, CA, USA).

    Techniques: Activity Assay, Derivative Assay, Inhibition