reference ido1 inhibitor epacadostat (BPS Bioscience)
Structured Review

Reference Ido1 Inhibitor Epacadostat, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/reference ido1 inhibitor epacadostat/product/BPS Bioscience
Average 90 stars, based on 1 article reviews
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1) Product Images from "Lichen-Derived Compounds and Extracts as Biologically Active Substances with Anticancer and Neuroprotective Properties"
Article Title: Lichen-Derived Compounds and Extracts as Biologically Active Substances with Anticancer and Neuroprotective Properties
Journal: Pharmaceuticals
doi: 10.3390/ph14121293
Figure Legend Snippet: Effect of the investigated lichen extracts and reference compounds on the activity of indoleamine-2,3-dioxygenase (IDO1, IDO2) and tryptophan-2,3-dioxygenase (TDO).
Techniques Used: Activity Assay, Inhibition
Figure Legend Snippet: The biological activity of lichen-derived compounds and extracts: compounds ( A ) and extracts ( B ), expressed by the surface of area, taking into account the measured biological properties expressed in %. The graphs were made for the concentrations: inhibition of IDO1 100.0 µg/mL ( A , B ); inhibition of COX-2 250.0 µg/mL ( A , B ); inhibition of hyaluronidase 500.0 µg/mL ( A , B ); inhibition of SOD 537.6 µg/mL ( A , B ); inhibition of GR 444.4 µg/mL ( A , B ); inhibition of GPx 243.9 µg/mL ( A , B ); cytotoxicity expressed as % of cell death: A-172 100 µM ( A ), 50 µg/mL ( B ), and T98G 100 µM ( A ), 50 µg/mL ( B ).
Techniques Used: Activity Assay, Derivative Assay, Inhibition